Mucormycosis: A rare infection being found commonly in Covid patients

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This condition may reach the proportion of the current epidemic because of Covid-19, but Mukormycosis has never been heard in India even in the pre-covid era

Health workers check on Covid-19 patients at Shehnai Banquet Hall, converted into an isolation centre, in New Delhi.
Health workers check on Covid-19 patients at Shehnai Banquet Hall, converted into an isolation centre, in New Delhi.

Apart from Pandemi Coronavirus (Covid-19) Pandemi, India also struggles with one serious complication called Mukormycosis or Black Mushroom.

Usually rare diseases, mukormycosis has been reported in thousands of positive individuals Covid-19 throughout the country. With many of them giving up on him, it has been declared an epidemic by countries such as Rajasthan. Black mushroom cases have shown a 50% death rate; Maharashtra has reported at least 50 deaths, and other countries, such as Madhya Pradesh, also reported death.

This condition can achieve the proportion of the current epidemic because of Covid-19, but mukormycosis has never been heard in India even in the pre-covid era. Because of the lack of population level data, the load may be unknown, but basing our knowledge of certain papers, and after talking to critical care experts, we can call it rare conditions.

“I can’t talk about the incidence of such diseases, but in our clinical life, we will see a maximum of five to seven patients like that in the intensive care unit. It’s rare,” said Dr. Anjan Trikha, Professor, Anesthetic Department, Critical Care and Medicine Pain, All Institutes of Indian Medicine (AIIMS), Delhi.

Although rarely, the incidence of Musormycosis for years has increased in India, finding a research paper entitled ‘Epidemiology of Mucormycosis in India’ published in March, 2021, in medical journal microorganisms.

This paper was written by Haripasih Prakash, the Department of Public Health, International Medical School, Kyrgyzstan, and Arunalasoke Chakrabarti, Head of the Ministry of Medical Microbiology, Institute of Education and Medical Research on Postgraduate, Chandigarh.

“Chakrabarti et al. Shows increased muctemic trends from one center in a consecutive period, with an annual incidence of 12.9 cases per year during 1990-1999, 35.6 cases per year during 2000-2004, and 50 cases per year during 2006-2007. The total number increased from 25 cases per year (1990-2007) to 89 cases per year (2013-2015), “said the author in the newspaper.

“… A multicenter study throughout India reported 465 cases from 12 centers of more than 21 months; this study reported an annual event of 22 cases per year, and an average of 38.8 cases for each participating center … without estimation based The population, it is difficult to determine the right incidence and the prevalence of mucatorcosis in the Indian population. Computational model-based methods estimate the prevalence of 14 cases per 100,000 individuals in India, “he added.

The incidence seems to have grown last year with Covid-19.

“Black fungal infection rose 2.5 times last year between September and December at 16 centers in the country,” said Dr. Chakrabarti earlier. He is part of the fungal infection study forum and is one of the members who compose government advisors about Mukormycosis management.

“We conducted research at 16 centers between September and December last year which showed that infection had increased by 2.5-fold. The possibility of going up further this time; we plan to hold another study,” he said.

According to his advisor that the unification of the Ministry of Health was released a few days ago, Mukormycosis mainly affected people who were taking medication for other health problems that reduce their ability to combat environmental pathogens.

Although it has not been determined whether the virus that causes Covid-19 is directly responsible for fostering cases, doctors also say several factors found in Covid-19 patients can lead to secondary infections.

“Mucormycosis requires fertile soil to grow, and high blood glucose levels, lack of oxygen, acidosis and immunity suppressed all contribute to growth. There is a probably all these factors in Covid-19 patients, maybe, leading to increasing cases [black mushrooms] , “said Dr. Ambrish Mithal, Chairperson, Department of Endocrinology and Diabetes, Max Healthcare.

Reaching hospitals late in many cases can cause death.

“There isn’t too much medicine to treat conditions, and in India, one of the main problems is patients who report late to hospitals that tend to change the results of care. But the reason fungus becomes pathological and growing in various parts of the body compromised immunity (people on people on High-dose steroids for a prolonged period) and uncontrolled diabetes, “added Dr. Trikha.

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